An Audit of the Stages of Spinal Cord Injury Pathogenesis and their Relation to Secondary Medical Complications and Potential Chronicity in Patients

An Audit of the Stages of Spinal Cord Injury Pathogenesis and their Relation to Secondary Medical Complications and Potential Chronicity in Patients

More than a decade ago, spinal-cord injury meant confinement to a wheelchair and a lifetime of medical comorbidity. The physician’s armamentarium of treatments was very limited, and provision of care for individuals with spinal-cord injury was usually met with...
Pathogenic Agents of Alzheimer’s Disease and Their Corresponding Pharmacotherapeutic Treatment Hypotheses

Pathogenic Agents of Alzheimer’s Disease and Their Corresponding Pharmacotherapeutic Treatment Hypotheses

Alzheimer’s Disease (AD), the most common cause of dementia, is a progressive and fatal neurodegenerative disorder that primarily affects older adults. Though the definitive etiology of the disease is still to be uncovered, several characteristic features of the...
The Etiology of Alzheimer’s Disease Reveals Potential Applications for Precision-Based Gene Therapy Utilizing the CRISPR/Cas9 Protocol To Counter Mechanisms of Pathogenesis

The Etiology of Alzheimer’s Disease Reveals Potential Applications for Precision-Based Gene Therapy Utilizing the CRISPR/Cas9 Protocol To Counter Mechanisms of Pathogenesis

The CRISPR-Cas9 genome-editing system is a part of the adaptive immune system in archaea and bacteria to defend against invasive nucleic acids from phages and plasmids. The guide RNA (sgRNA) of the system recognizes its target sequence in the genome, and the Cas9...
Epidemiological Analysis of the Relationship Between Lower Back Pain Incidence and Implementation of Occupational Preventative Measures

Epidemiological Analysis of the Relationship Between Lower Back Pain Incidence and Implementation of Occupational Preventative Measures

Roughly 60 to 80% of individuals in the United States population have experienced lower back pain at some point in their life [1]. Lower back pain (LBP) is generally defined as pain, muscle tension, or stiffness localised below the costal margin and above the inferior...