Pathogenic Agents of Alzheimer’s Disease and Their Corresponding Pharmacotherapeutic Treatment Hypotheses

Pathogenic Agents of Alzheimer’s Disease and Their Corresponding Pharmacotherapeutic Treatment Hypotheses

Alzheimer’s Disease (AD), the most common cause of dementia, is a progressive and fatal neurodegenerative disorder that primarily affects older adults. Though the definitive etiology of the disease is still to be uncovered, several characteristic features of the...
The Etiology of Alzheimer’s Disease Reveals Potential Applications for Precision-Based Gene Therapy Utilizing the CRISPR/Cas9 Protocol To Counter Mechanisms of Pathogenesis

The Etiology of Alzheimer’s Disease Reveals Potential Applications for Precision-Based Gene Therapy Utilizing the CRISPR/Cas9 Protocol To Counter Mechanisms of Pathogenesis

The CRISPR-Cas9 genome-editing system is a part of the adaptive immune system in archaea and bacteria to defend against invasive nucleic acids from phages and plasmids. The guide RNA (sgRNA) of the system recognizes its target sequence in the genome, and the Cas9...
ACL Recovery Inequality: Socioeconomic Status and Injury Recuperation

ACL Recovery Inequality: Socioeconomic Status and Injury Recuperation

Anterior cruciate ligament (ACL) injury is commonplace amongst athletes and individuals alike, yet despite its frequency, this injury devastatingly increases morbidity and greatly impacts one’s day-to-day schedule (1). ACL injuries comprise up to 50% of ligamentous...
Racial Disparities in Individuals Presenting with Knee Injuries Seeking Total Knee Arthroplasty/Total Joint Replacement Procedures

Racial Disparities in Individuals Presenting with Knee Injuries Seeking Total Knee Arthroplasty/Total Joint Replacement Procedures

Total Knee Arthroplasty (TKA) and Total Joint Replacement (TJR) procedures are customarily used to surgically reconstruct or replace a joint. This procedure is frequently performed as a resolution for functional debilitation in the knee and knee pain management....