The Etiology of Alzheimer’s Disease Reveals Potential Applications for Precision-Based Gene Therapy Utilizing the CRISPR/Cas9 Protocol To Counter Mechanisms of Pathogenesis

The Etiology of Alzheimer’s Disease Reveals Potential Applications for Precision-Based Gene Therapy Utilizing the CRISPR/Cas9 Protocol To Counter Mechanisms of Pathogenesis

The CRISPR-Cas9 genome-editing system is a part of the adaptive immune system in archaea and bacteria to defend against invasive nucleic acids from phages and plasmids. The guide RNA (sgRNA) of the system recognizes its target sequence in the genome, and the Cas9...
Racial Disparities in Individuals Presenting with Knee Injuries Seeking Total Knee Arthroplasty/Total Joint Replacement Procedures

Racial Disparities in Individuals Presenting with Knee Injuries Seeking Total Knee Arthroplasty/Total Joint Replacement Procedures

Total Knee Arthroplasty (TKA) and Total Joint Replacement (TJR) procedures are customarily used to surgically reconstruct or replace a joint. This procedure is frequently performed as a resolution for functional debilitation in the knee and knee pain management....
Orthopedic regenerative medicine

Orthopedic regenerative medicine

A new area of medicine that has sparked interest in orthopedics is regenerative medicine. Great hopes are set on regenerative medicine to develop alternative therapies for cartilage damage, arthritis, large bone defects, and tendon ruptures. Stem cells are of...
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