by Sharen Singh | Jun 3, 2021 | Alzheimer's Disease, I. Issues, II. Roles, Medical Officers
Increasing evidence suggests that Alzheimer’s disease pathogenesis is not restricted to the neuronal compartment, but includes strong interactions with immunological mechanisms in the brain. Misfolded and aggregated proteins bind to pattern recognition receptors...
by Sharen Singh | Apr 16, 2021 | Alzheimer's Disease, I. Issues, II. Roles, Medical Officers, Physical Therapy / Medicine and Rehabilitation, Prescribers
Alzheimer’s Disease (AD), the most common cause of dementia, is a progressive and fatal neurodegenerative disorder that primarily affects older adults. Though the definitive etiology of the disease is still to be uncovered, several characteristic features of the...
by Sharen Singh | Apr 9, 2021 | Alzheimer's Disease, I. Issues, II. Roles, IV. Others, Medical Officers
The CRISPR-Cas9 genome-editing system is a part of the adaptive immune system in archaea and bacteria to defend against invasive nucleic acids from phages and plasmids. The guide RNA (sgRNA) of the system recognizes its target sequence in the genome, and the Cas9...
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